The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 55, 71-78, Copyright, 1932, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE EPIDEMIOLOGY OF FOWL CHOLERA : VI. THE SPREAD OF EPIDEMIC AND ENDEMIC STRAINS OF PASTEURELLA AVICIDA IN LABORATORY POPULATIONS OF NORMAL FOWL



I. W. Pritchett Sc.D.1 and T. P. Hughes Ph.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

1. Strains of-P. avicida from "spontaneous epidemics" of fowl cholera, when introduced intranasally in fixed doses into specially bred chickens, induced fatal fowl cholera in about 40 per cent but did not survive in the nasal clefts of resistant birds nor spread to normal contacts.

2. Strains of P. avicida from "spontaneous endemics" of fowl cholera, when introduced similarly into chickens, failed to kill but did survive in the nasal clefts of inoculated birds and spread readily to normal contacts.

3. "Laboratory" variants of the epidemic strains of P. avicida failed to kill or survive in the test birds and did not spread to contacts.

Submitted on September 21, 1931


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