The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 54, 499-514, Copyright, 1931, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE GRADIENT OF VASCULAR PERMEABILITY : IV. THE PERMEABILITY OF THE CUTANEOUS VENULES AND ITS FUNCTIONAL SIGNIFICANCE



Frederick Smith M.B., B.Ch.1 and Peyton Rous M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

The permeability of the venules of the skin of the mouse greatly exceeds that of the capillaries. A mounting gradient of permeability exists along the further portion of the latter.

The significance of these facts is discussed with relation to conditions in human skin. The cutaneous venules are differentiated for several functions besides those ordinarily attributed to them, and must be considered as specialized organs.

Submitted on June 26, 1931


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