The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 54, 453-461, Copyright, 1931, by The Rockefeller Institute for Medical Research New York

ARTICLE

CULTIVATION OF VACCINE VIRUS FOR JENNERIAN PROPHYLAXIS IN MAN

T. M. Rivers M.D.1 and With the Technical Assistance of S. M. Ward

1 From the Hospital of The Rockefeller Institute for Medical Research

1. A dermal strain of vaccine virus has been adapted to a simple culture medium consisting of minced chick embryo suspended in Tyrode's solution.

2. The bacteria-free culture virus, thus obtained, produces in lower animals and in man typical vaccinia that renders them refractory to infection with ordinary vaccine virus harvested from calves.

 Submitted on June 14, 1931


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