The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 53, 447-470, Copyright, 1931, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE ETIOLOGY OF ACUTE UPPER RESPIRATORY INFECTION (COMMON COLD)

Perrin H. Long M.D.1, James A. Doull M.D.1, Janet M. Bourn Ph.D.1, and Emily McComb Ph.D.1

1 From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore

Experimental upper respiratory infections similar to "common colds" were transmitted singly and in series through two and four passages in nine out of fifteen persons, by intransal inoculations with bacteria-free filtrates of nasopharyngeal washings obtained from individuals ill with natural "colds." These observations conform with those reported by previous workers and lend further support to the view that the incitant of the "common cold" is a filtrable virus.

Submitted on December 28, 1930


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