The Journal of Experimental Medicine
Randox clinical diagnostic solutions
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The Journal of Experimental Medicine, Vol 53, 317-324, Copyright, 1931, by The Rockefeller Institute for Medical Research New York

ARTICLE

COMPENSATORY HYPERTROPHY OF THE SPLEEN

Eaton M. MacKay M.D.1 and W. Scott Polland M.D.1

1 From the Department of Medicine, Stanford University Medical School, San Francisco

Following the removal of half of the spleen in young adult rats there is a compensatory enlargement of the remaining portion of about 50 per cent while in mature rabbits no such compensatory hypertrophy follows a similar procedure. It is uncertain whether this difference is due to a difference in the function of the spleen in the two species or to the fact that the rats were infected with Bartonella muris while the rabbits were not.

Submitted on November 30, 1930


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