The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 52, 769-780, Copyright, 1930, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE KILLING OF COLON BACILLI BY X-RAYS OF DIFFERENT WAVE LENGTHS

Ralph W. G. Wyckoff Ph.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research

X-ray beams of wave lengths lying in the range between 4 A and 0.5 A all kill B. coli in a semilogarithmically linear fashion. Interpreted in terms of the known quantized absorption of X-rays, this means that one absorption of any of these radiations is sufficient to kill. Though death results from a single absorption, only about one hit in four with Ag K and one in sixty with Ag L radiation is deadly. The course of curves constructed from these experimental results suggests that the portion of this bacterium which is essential to its continued life has a total of approximately 0.01 of the cell volume.

For copper and harder radiations the biological action of the rays is proportional to their measured air ionization. The same biological change with the softer chromium K. and silver L X-rays seems to require a somewhat more intensely ionizing beam.

 Submitted on July 13, 1930


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