The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 42, 123-142, Copyright, 1925, by The Rockefeller Institute for Medical Research New York

ARTICLE

ON THE ANTIGENS OF RED BLOOD CORPUSCLES : II. FLOCCULATION REACTIONS WITH ALCOHOLIC EXTRACTS OF ERYTHROCYTES.



K. Landsteiner M.D.1 and James van der Scheer 1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

1. Flocculation reactions of anti-erythrocyte sera on emulsions of alcoholic extract of blood are described.

2. The reactions are markedly species-specific.

3. Besides the homologous reactions certain others—"heterogenetic"" ones—have been observed, and in this way the existence of new examples of heterogenetic antibodies has been demonstrated.

4. Group-specific substances can be extracted from human erythrocytes with alcohol and demonstrated by flocculation with group-specific immune sera.

5. A conception of the structure of cellular antigens based upon the known facts, is presented.

 Submitted on May 13, 1925


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