The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 41, 285-298, Copyright, 1925, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VIII. NATURE OF THE OXIDATION-REDUCTION SYSTEMS IN STERILE PNEUMOCOCCUS EXTRACTS.



James M. Neill Ph.D.1 and Oswald T. Avery M.D.1

1 From the Hospital of The Rockefeller Institute for Medical Research.

1. The systems responsible for oxidation and reduction in the pneumococcus cell have been shown to consist of two components, the nature of which has been discussed.

2. The oxidizing and reducing power of active extracts of pneumococci is inactivated by exposure to air. This loss in activity is due to an inactivation of the thermolabile cellular component consequent on secondary reactions analogous to those which under similar conditions destroy the hemotoxin and enzymes in pneumococcus extracts.

 Submitted on December 3, 1924


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