The Journal of Experimental Medicine
Cytokines in immune regulation
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The Journal of Experimental Medicine, Vol 41, 113-117, Copyright, 1925, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE DISTRIBUTION OF CHLORIDES IN THE BLOOD OF THE DOG AFTER EXPERIMENTAL INTESTINAL OBSTRUCTION

Russell L. Haden M.D.1 and Thomas G. Orr M.D.1

1 From the University of Kansas School of Medicine, Kansas City, Kansas.

The results of simultaneous chloride determinations in whole blood, in plasma, and in cells of the dog after experimental intestinal obstruction are presented, and the chloride content of whole blood and of plasma is compared by two methods of estimation: the iodometric titration on protein-free filtrate, and the digestion technique of Van Slyke.

The chloride as determined on protein-free filtrate checks closely with that as determined by the digestion procedure. The iodometric determination shows accurately the level of chlorides in the blood. The total change in the chloride store of the body is best reflected in determinations on whole blood.

In intestinal obstruction the retained chloride is not present in the blood in some undetermined form.

Submitted on August 12, 1924


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