The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 40, 619-625, Copyright, 1924, by The Rockefeller Institute for Medical Research New York


ARTICLE

THE INFLUENCE OF THE SUPRARENAL GLAND ON THE THYMUS : II. DIRECT EVIDENCE OF REGENERATION OF THE INVOLUTED THYMUS FOLLOWING DOUBLE SUPRARENALECTOMY IN THE RAT.



Henry L. Jaffe M.D.1

1 From the Laboratory Division of Montefiore Hospital, New York.

1. Regeneration of involuted thymuses of old rats follows double suprarenalectomy in this species with great constancy.

2. Partial thymectomy alone does not induce compensatory secondary hyperplasia in involuting glands.

3. Regeneration of the thymus following suprarenalectomy would appear to be completed in most rats in about 2 weeks; and it probably begins in the medulla.

Submitted on June 29, 1924


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