The Journal of Experimental Medicine
Cytokines Montreal 2008
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The Journal of Experimental Medicine, Vol 38, 707-711, Copyright, 1923, by The Rockefeller Institute for Medical Research New York

ARTICLE

A STUDY OF THE FACTORS UNDERLYING THE FORMATION OF ALVEOLAR PORES IN PNEUMONIA

William Snow Miller M.D.1

1 From the Anatomical Laboratory of the University of Wisconsin, Madison.

The epithelium lining the alveolar walls is a continuous epithelium.

In both inflammatory and mechanical congestion of the pulmonary blood vessels, it is the accumulation of serum behind the epithelial cells which causes them to be shed.

The epithelium must be shed from diametrically opposite sides of an alveolar wall before a "pore" can be formed.

In both lobar pneumonia and mechanical edema pores are present, but they are not normal structures.

 Submitted on July 18, 1923


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