The Journal of Experimental Medicine
Avanti Polar Lipids
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The Journal of Experimental Medicine, Vol 38, 93-106, Copyright, 1923, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE INFLUENCE OF THE SUPRARENAL CORTEX ON THE GONADS OF RABBITS : I. THE EFFECTS OF SUPRARENAL INJURY (BY REMOVAL OR FREEZING) ON THE INTERSTITIAL CELLS OF THE OVARY.



Henry L. Jaffe M.D.1 and David Marine M.D.1

1 From the Division of Laboratories of Montefiore Hospital and the Department of Pathology of Columbia University, New York.

1. Moderate or marked ovarian enlargement has been observed in 76 per cent of rabbits which survived double suprarenalectomy over 30 days.

2. The ovarian enlargement consists essentially of an hypertrophy of the interstitial cells.

3. The hypertrophy of the interstitial cells is a compensatory reaction and adds further data to the functional interrelation between the suprarenal cortex and the interstitial cells.

 Submitted on February 25, 1923


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