The Journal of Experimental Medicine
Cytokines Montreal 2008
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The Journal of Experimental Medicine, Vol 36, 219-230, Copyright, 1922, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE EXPERIMENTAL PRODUCTION OF PERIARTERITIS NODOSA IN THE RABBIT WITH A CONSIDERATION OF THE SPECIFIC CAUSAL EXCITANT

William H. Harris M.D.1 and Andrew V. Friedrichs M.D.1

1 From the Department of Pathology of Tulane University of Louisiana, New Orleans.

1. Periarteritis nodosa is a specific infectious disease which is transmissible to the rabbit.

2. The lesions induced in rabbits are identical with those occurring in man and consist of exudative and degenerative processes within the walls of the smaller arteries resulting in aneurysmal formations and thromboses.

3. The microorganism inducing the disease is capable of going through a Berkefeld N filter and is therefore to be classed with the group of so called filter passers.

 Submitted on February 13, 1922


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