The Journal of Experimental Medicine
Torrey Pines Biolabs
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The Journal of Experimental Medicine, Vol 36, 199-217, Copyright, 1922, by The Rockefeller Institute for Medical Research New York

ARTICLE

INFLUENCE OF GLANDS WITH INTERNAL SECRETION ON THE RESPIRATORY EXCHANGE : IV. EFFECT OF SUPRARENAL INSUFFICIENCY IN CATS.



W. J. M. Scott M.D.1

1 From the Laboratories of Montefiore Hospital, and the Department of Pathology of Columbia University, New York.

1. Severe and sufficient non-fatal injury to the suprarenal cortex by freezing or by ligation in cats causes a significant and prolonged increase in heat production.

2. Lethal injury to the suprarenals by freezing, ligation, or partial excision in cats causes a fall in heat production.

3. Insufficient injury to the suprarenals by freezing, ligation, or partial excision in cats produces no significant alteration in heat production.

4. Further evidence of a dose thyroid-suprarenal cortex interrelationship is indicated by the rapidity of thyroid hyperplasia and by the effects of KI after suprarenal crippling.

 Submitted on March 20, 1922


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