The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 35, 703-706, Copyright, 1922, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE PNEUMOCOCCUS : IV. EFFECT OF BILE AT VARYING HYDROGEN ION CONCENTRATIONS ON DISSOLUTION OF PNEUMOCOCCI.



Frederick T. Lord M.D.1 and Robert N. Nye M.D.1

1 From the Research Laboratory of the Massachusetts General Hospital, Boston.

Dissolution of pneumococci takes place most rapidly in bile at a slightly alkaline reaction. This is probably due to death of the organisms and activation of the endocellular enzyme at its optimum hydrogen ion concentration.

Submitted on December 15, 1921


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