The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 35, 487-492, Copyright, 1922, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON X-RAY EFFECTS : XI. THE FATE OF CANCER GRAFTS IMPLANTED IN SUBCUTANEOUS TISSUE PREVIOUSLY EXPOSED TO X-RAYS.



J. Heng Liu M.D.1, Ernest Sturm 1, and James B. Murphy M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

An erythema dose of x-rays given direct to the exposed subcutaneous tissue and muscle greatly diminishes the susceptibility of the exposed area to transplanted cancer. The same dose given over the intact skin does not affect the resisting power of the underlying subcutaneous tissue.

Histological examination shows that a few days after the exposure of the subcutaneous tissue there is a lymphoid infiltration of this tissue, which infiltration sometimes includes the muscle layers as well.

 Submitted on November 21, 1921


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