The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 34, 397-405, Copyright, 1921, by The Rockefeller Institute for Medical Research New York

ARTICLE

WANDERING CELLS, ENDOTHELIAL CELLS, AND FIBROBLASTS IN CULTURES FROM HUMAN LYMPH NODES

Warren H. Lewis M.D.1 and Leslie T. Webster M.D.1

1 From the Department of Embryology of Carnegie Institution of Washington and the Department of Pathology of Johns Hopkins Medical School, Baltimore.

Wandering cells migrate from cultures of human lymph nodes after 2 or 3 hours incubation; they are actively ameboid and phagocytic.

Endothelial cells appear in the plasma clot after 24 to 48 hours incubation. They are relatively inactive and less phagocytic.

Fibroblasts are seen after 48 hours incubation. They are inactive and not phagocytic.

The probable origin of wandering cells from endothelial cells is discussed.

 Submitted on April 21, 1921


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