The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 34, 199-200, Copyright, 1921, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON THE PNEUMONIC EXUDATE : I. EFFECT OF PRESERVATION, TEMPERATURE, DIALYSIS, AND SALT CONCENTRATION ON THE ENZYME IN THE PNEUMONIC LUNG.



Frederick T. Lord M.D.1 and Robert N. Nye M.D.1

1 From the Research Laboratory of the Massachusetts General Hospital, Boston.

1. The enzyme present in the pneumonic lung exudate still remains active after preservation for 18 months.

2. The enzyme is active at incubator temperature before and after heating to 65°C. for 1 hour. It is slightly active at room temperature and inactive after heating at 75°C. for 1 hour.

3. Dialysis of the enzyme is not demonstrable.

4. Activity persists when the enzyme is mixed with concentrations of sodium chloride varying from normal to thirty-two times normal.

 Submitted on March 27, 1921


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