The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 34, 185-188, Copyright, 1921, by The Rockefeller Institute for Medical Research New York

ARTICLE

NOTE ON THE PRESERVATION OF STOCK STRAINS OF TREPONEMA PALLIDUM AND ON THE DEMONSTRATION OF INFECTION IN RABBITS

Wade H. Brown M.D.1 and Louise Pearce M.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

Experiments carried out on rabbits infected with Treponema pallidum showed that there was a constant invasion and localization of the organisms in the superficial lymph nodes, that the infection persisted indefinitely, and that organisms could be recovered at any time from such nodes as the popliteals. Based upon these observations, a method is proposed for the preservation or recovery of stock strains of Treponema pallidum and for the demonstration of infection in rabbits.

Submitted on March 1, 1921


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