The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 29, 83-87, Copyright, 1919, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON X-RAY EFFECTS : III. CHANGES IN THE LYMPHOID ORGANS AFTER SMALL DOSES OF X-RAYS.



Waro Nakahara Ph.D.1

1 From the Laboratories of The Rockefeller Institute for Medical Research.

1. The small dose of x-rays applied to the rabbit has no appreciable destructive effect on the lymphoid tissue.

2. Indications of stimulation of the lymphoid tissue appear immediately after the treatment, become most pronounced in 2 (in lymph glands) to 4 (in the spleen) days, and persist, in a slight degree, up to the 14th day.

3. These facts suggest that the lymphocytosis induced by the small dose of x-rays is due to a primary stimulative effect upon the lymphoid tissue of the animal.

 Submitted on October 21, 1918


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