The Journal of Experimental Medicine
StemCell Technologies
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
Published online January 14, 2008
doi:10.1084/jem.20072665
The Journal of Experimental Medicine, Vol. 205, No. 1, 13-17
The Rockefeller University Press, 0022-1007 $30.00
© 2008 MacDonald et al.
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Citation Map
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Google Scholar
Right arrow Articles by MacDonald, A. S.
Right arrow Articles by Maizels, R. M.
PubMed
Right arrow PubMed Citation
Right arrow Articles by MacDonald, A. S.
Right arrow Articles by Maizels, R. M.
Related Collections
Right arrowRelated Article
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?

COMMENTARY

 Alarming dendritic cells for Th2 induction

Andrew S. MacDonald and Rick M. Maizels

A.S. MacDonald and R.M. Maizels are at the Institute of Immunology and Infection Research, Ashworth Laboratories, University of Edinburgh, Edinburgh EH9 3JT, Scotland, UK

CORRESPONDENCE R.M.M.: rick.maizels{at}ed.ac.uk OR A.S.M.: andrew.macdonald{at}ed.ac.uk


ABSTRACT
There is an ever-increasing understanding of the mechanisms by which pathogens such as bacteria, viruses, and protozoa activate dendritic cells (DCs) to drive T helper type 1 (Th1) responses, but we know much less about how these cells elicit Th2 responses. This gap in our knowledge puts us at a distinct disadvantage in designing therapeutics for certain immune-mediated diseases. However, progress is being made with the identification of novel endogenous tissue factors that can enhance Th2 induction by DCs.


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?

Related Article

Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2–MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
De Yang, Qian Chen, Shao Bo Su, Ping Zhang, Kahori Kurosaka, Rachel R. Caspi, Suzanne M. Michalek, Helene F. Rosenberg, Ning Zhang, and Joost J. Oppenheim
J. Exp. Med. 2008 205: 79-90. [Abstract] [Full Text] [PDF]





  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS