The Journal of Experimental Medicine
Randox
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Published online March 19, 2007
doi:10.1084/jem.2043fta
The Journal of Experimental Medicine, Vol. 204, No. 3, 459-
The Rockefeller University Press, 0022-1007 $30.00
© 2007 Bashyam
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FROM THE ARCHIVE

 Crossing barriers in transplantation

Hema Bashyam, JEM News Editor

hbashyam{at}rockefeller.edu


ABSTRACT
In 1978, Jonathan Sprent and Robert Korngold proved that graft-versus-host disease (GVHD) is caused by donor T cells that attack the host's non-MHC antigens. T cell depletion of donor grafts has since become a staple of transplantation strategies to combat leukemia and other inherited blood disorders.


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