The Journal of Experimental Medicine
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Published online December 17, 2007
doi:10.1084/jem.20413fta
The Journal of Experimental Medicine, Vol. 204, No. 13, 3057-
The Rockefeller University Press, 0022-1007 $30.00
© 2007 Ruttimann
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FROM THE ARCHIVE

 Macrophages and nitric oxide: A deadly combination

Jacqueline Ruttimann

jruttimann{at}gmail.com


ABSTRACT
In the late 1980s, Carl Nathan and colleagues pinpointed nitric oxide (NO) as a molecule that macrophages use to kill tumor cells. This discovery helped verify the role of radicals as signaling molecules in the immune system.


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