Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents

This Article Full Text Full Text (PDF) PPT slides of all figures Alert me when this article is cited Citation Map Services Email this article Similar articles in this journal Similar articles in PubMed Alert me to new content in the JEM Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by Tracey, K. J. Search for Related Content PubMed PubMed Citation Articles by Tracey, K. J. Social Bookmarking                      What's this?

K.J.T. is at North Shore-LIJ Research Institute, Manhassset, NY 11030.

CORRESPONDENCE K.J.T.: kjtracey{at}nshs.edu

Abstract
The cholinergic antiinflammatory pathway is a neural mechanism that is controlled by the vagus nerve and inhibits local cytokine release, thereby preventing the damaging effects of cytokine overproduction. A new study now shows that dietary fat can activate this pathway, a finding that may help explain the immune system's failure to react to food antigens and commensal bacteria. Here we discuss this new data and its potential implications for dietary intervention in the treatment of inflammatory diseases.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati

This article has been cited by other articles:

• Moran, G. W., Leslie, F. C., Levison, S. E., McLaughlin, J. T. (2008). Review: Enteroendocrine cells: Neglected players in gastrointestinal disorders?. Therapeutic Advances in Gastroenterology 1: 51-60 [Abstract]  
• Oke, S. L., Tracey, K. J. (2008). From CNI-1493 to the immunological homunculus: physiology of the inflammatory reflex. J. Leukoc. Biol. 83: 512-517 [Abstract] [Full Text]  
• Kavoussi, B., Ross, B. E. (2007). The Neuroimmune Basis of Anti-inflammatory Acupuncture. Integr Cancer Ther 6: 251-257 [Abstract]  
• Mravec, B. (2007). Letter To the Editor: Autonomic dysfunction in autoimmune diseases: consequence or cause?. Lupus 16: 767-768  
• Pena-Philippides, J. C., Razani-Boroujerdi, S., Singh, S. P., Langley, R. J., Mishra, N. C., Henderson, R. F., Sopori, M. L. (2007). Long- and Short-Term Changes in the Neuroimmune-Endocrine Parameters following Inhalation Exposures of F344 Rats to Low-Dose Sarin. Toxicol Sci 97: 181-188 [Abstract] [Full Text]  
• Tracey, K. J. (2005). Fat meets the cholinergic antiinflammatory pathway. J. Cell Biol. 171: i6-i6 [Full Text]  
• Tracey, K. J. (2005). Fat meets the cholinergic antiinflammatory pathway. J. Cell Biol. 171: i3-i3 [Full Text]  

Home | Help | Feedback | Subscriptions | Archive | Search

TABLE OF CONTENTS