The Journal of Experimental Medicine
Keystone Symposia
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Published 5 December 2005. doi:10.1084/jem.20052211
Rockefeller University Press, 0022-1007 $8.00
JEM, Volume 202, Number 11, 1459-1463
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COMMENTARY

Regulatory T cells and IL-10 in allergic inflammation

Catherine M. Hawrylowicz

C.M.H. is at the Medical Research Council and Asthma UK Centre for Allergic Mechanisms in Asthma, King's College London, London SE1 9RT, UK.

CORRESPONDENCE C.M.H.catherine.hawrylowicz{at}kcl.ac.uk


Abstract
Recent studies suggest that human regulatory T (T reg) cells protect against the development of allergic and asthmatic disease and that their function is impaired during active disease. Two new studies contribute to our understanding of the role that T reg cells play in the control of allergic airway disease in mice. However, these studies also highlight several outstanding questions in the field.



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