Noda, S., Horiguchi, K., Ichikawa, H., Miyoshi, H.
(2008). Repopulating Activity of Ex Vivo-Expanded Murine Hematopoietic Stem Cells Resides in the CD48-c-Kit+Sca-1+Lineage Marker- Cell Population. Stem Cells
26: 646-655
[Abstract][Full Text]
Diermayr, S., Himmelreich, H., Durovic, B., Mathys-Schneeberger, A., Siegler, U., Langenkamp, U., Hofsteenge, J., Gratwohl, A., Tichelli, A., Paluszewska, M., Wiktor-Jedrzejczak, W., Kalberer, C. P., Wodnar-Filipowicz, A.
(2008). NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities. Blood
111: 1428-1436
[Abstract][Full Text]
Zhang, X.-B., Schwartz, J. L., Humphries, R. K., Kiem, H.-P.
(2007). Effects of HOXB4 Overexpression on Ex Vivo Expansion and Immortalization of Hematopoietic Cells from Different Species. Stem Cells
25: 2074-2081
[Abstract][Full Text]
Kang, Y.-J., Yang, S.-J., Park, G., Cho, B., Min, C.-K., Kim, T.-Y., Lee, J.-S., Oh, I.-H.
(2007). A Novel Function of Interleukin-10 Promoting Self-Renewal of Hematopoietic Stem Cells. Stem Cells
25: 1814-1822
[Abstract][Full Text]
Kimura, T., Asada, R., Wang, J., Kimura, T., Morioka, M., Matsui, K., Kobayashi, K., Henmi, K., Imai, S., Kita, M., Tsuji, T., Sasaki, Y., Ikehara, S., Sonoda, Y.
(2007). Identification of Long-Term Repopulating Potential of Human Cord Blood-Derived CD34-flt3- Severe Combined Immunodeficiency-Repopulating Cells by Intra-Bone Marrow Injection. Stem Cells
25: 1348-1355
[Abstract][Full Text]
Araki, H., Yoshinaga, K., Boccuni, P., Zhao, Y., Hoffman, R., Mahmud, N.
(2007). Chromatin-modifying agents permit human hematopoietic stem cells to undergo multiple cell divisions while retaining their repopulating potential. Blood
109: 3570-3578
[Abstract][Full Text]
McKenzie, J. L., Takenaka, K., Gan, O. I., Doedens, M., Dick, J. E.
(2007). Low rhodamine 123 retention identifies long-term human hematopoietic stem cells within the Lin-CD34+CD38- population. Blood
109: 543-545
[Abstract][Full Text]
Vanheusden, K., Van Coppernolle, S., De Smedt, M., Plum, J., Vandekerckhove, B.
(2007). In Vitro Expanded Cells Contributing to Rapid Severe Combined Immunodeficient Repopulation Activity Are CD34+38-33+90+45RA-. Stem Cells
25: 107-114
[Abstract][Full Text]
Tanaka, H., Matsumura, I., Itoh, K., Hatsuyama, A., Shikamura, M., Satoh, Y., Heike, T., Nakahata, T., Kanakura, Y.
(2006). HOX Decoy Peptide Enhances the Ex Vivo Expansion of Human Umbilical Cord Blood CD34+ Hematopoietic Stem Cells/Hematopoietic Progenitor Cells. Stem Cells
24: 2592-2602
[Abstract][Full Text]
Suzuki, T., Yokoyama, Y., Kumano, K., Takanashi, M., Kozuma, S., Takato, T., Nakahata, T., Nishikawa, M., Sakano, S., Kurokawa, M., Ogawa, S., Chiba, S.
(2006). Highly Efficient Ex Vivo Expansion of Human Hematopoietic Stem Cells Using Delta1-Fc Chimeric Protein. Stem Cells
24: 2456-2465
[Abstract][Full Text]
Chen, X., Xu, H., Wan, C., McCaigue, M., Li, G.
(2006). Bioreactor Expansion of Human Adult Bone Marrow-Derived Mesenchymal Stem Cells. Stem Cells
24: 2052-2059
[Abstract][Full Text]
Chute, J. P., Muramoto, G. G., Whitesides, J., Colvin, M., Safi, R., Chao, N. J., McDonnell, D. P.
(2006). Inhibition of aldehyde dehydrogenase and retinoid signaling induces the expansion of human hematopoietic stem cells. Proc. Natl. Acad. Sci. USA
103: 11707-11712
[Abstract][Full Text]
Yeoh, J. S.G., van Os, R., Weersing, E., Ausema, A., Dontje, B., Vellenga, E., de Haan, G.
(2006). Fibroblast Growth Factor-1 and -2 Preserve Long-Term Repopulating Ability of Hematopoietic Stem Cells in Serum-Free Cultures. Stem Cells
24: 1564-1572
[Abstract][Full Text]
Bowles, K. M., Vallier, L., Smith, J. R., Alexander, M. R. J., Pedersen, R. A.
(2006). HOXB4 Overexpression Promotes Hematopoietic Development by Human Embryonic Stem Cells. Stem Cells
24: 1359-1369
[Abstract][Full Text]
Ando, K., Yahata, T., Sato, T., Miyatake, H., Matsuzawa, H., Oki, M., Miyoshi, H., Tsuji, T., Kato, S., Hotta, T.
(2006). Direct evidence for ex vivo expansion of human hematopoietic stem cells. Blood
107: 3371-3377
[Abstract][Full Text]
Miyake, N., Brun, A. C.M., Magnusson, M., Miyake, K., Scadden, D. T., Karlsson, S.
(2006). HOXB4-Induced Self-Renewal of Hematopoietic Stem Cells Is Significantly Enhanced by p21 Deficiency. Stem Cells
24: 653-661
[Abstract][Full Text]
Hess, D. A., Wirthlin, L., Craft, T. P., Herrbrich, P. E., Hohm, S. A., Lahey, R., Eades, W. C., Creer, M. H., Nolta, J. A.
(2006). Selection based on CD133 and high aldehyde dehydrogenase activity isolates long-term reconstituting human hematopoietic stem cells. Blood
107: 2162-2169
[Abstract][Full Text]
Delaney, C., Varnum-Finney, B., Aoyama, K., Brashem-Stein, C., Bernstein, I. D.
(2005). Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells. Blood
106: 2693-2699
[Abstract][Full Text]
Tavor, S., Petit, I., Porozov, S., Goichberg, P., Avigdor, A., Sagiv, S., Nagler, A., Naparstek, E., Lapidot, T.
(2005). Motility, proliferation, and egress to the circulation of human AML cells are elastase dependent in NOD/SCID chimeric mice. Blood
106: 2120-2127
[Abstract][Full Text]
Dorsch, M., Qiu, Y., Soler, D., Frank, N., Duong, T., Goodearl, A., O'Neil, S., Lora, J., Fraser, C. C.
(2005). PK1/EG-VEGF induces monocyte differentiation and activation. J. Leukoc. Biol.
78: 426-434
[Abstract][Full Text]
Basu, S., Broxmeyer, H. E.
(2005). Transforming growth factor-{beta}1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/CXCL12. Blood
106: 485-493
[Abstract][Full Text]
Wang, L., Menendez, P., Shojaei, F., Li, L., Mazurier, F., Dick, J. E., Cerdan, C., Levac, K., Bhatia, M.
(2005). Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J. Exp. Med.
201: 1603-1614
[Abstract][Full Text]
Srour, E. F., Tong, X., Sung, K. W., Plett, P. A., Rice, S., Daggy, J., Yiannoutsos, C. T., Abonour, R., Orschell, C. M.
(2005). Modulation of in vitro proliferation kinetics and primitive hematopoietic potential of individual human CD34+CD38-/lo cells in G0. Blood
105: 3109-3116
[Abstract][Full Text]
Byk, T., Kahn, J., Kollet, O., Petit, I., Samira, S., Shivtiel, S., Ben-Hur, H., Peled, A., Piacibello, W., Lapidot, T.
(2005). Cycling G1 CD34+/CD38+ Cells Potentiate the Motility and Engraftment of Quiescent G0 CD34+/CD38-/low Severe Combined Immunodeficiency Repopulating Cells. Stem Cells
23: 561-574
[Abstract][Full Text]
Chadwick, K., Shojaei, F., Gallacher, L., Bhatia, M.
(2005). Smad7 alters cell fate decisions of human hematopoietic repopulating cells. Blood
105: 1905-1915
[Abstract][Full Text]
Yang, L., Dybedal, I., Bryder, D., Nilsson, L., Sitnicka, E., Sasaki, Y., Jacobsen, S. E. W.
(2005). IFN-{gamma} Negatively Modulates Self-Renewal of Repopulating Human Hemopoietic Stem Cells. J. Immunol.
174: 752-757
[Abstract][Full Text]
Chute, J. P., Muramoto, G. G., Fung, J., Oxford, C.
(2005). Soluble factors elaborated by human brain endothelial cells induce the concomitant expansion of purified human BM CD34+CD38- cells and SCID-repopulating cells. Blood
105: 576-583
[Abstract][Full Text]
Hess, D. A., Meyerrose, T. E., Wirthlin, L., Craft, T. P., Herrbrich, P. E., Creer, M. H., Nolta, J. A.
(2004). Functional characterization of highly purified human hematopoietic repopulating cells isolated according to aldehyde dehydrogenase activity. Blood
104: 1648-1655
[Abstract][Full Text]
Summers, Y. J., Heyworth, C. M., de Wynter, E. A., Hart, C. A., Chang, J., Testa, N. G.
(2004). AC133+ G0 Cells from Cord Blood Show a High Incidence of Long-Term Culture-Initiating Cells and a Capacity for More Than 100 Million-Fold Amplification of Colony-Forming Cells In Vitro. Stem Cells
22: 704-715
[Abstract][Full Text]
Bruno, S., Gunetti, M., Gammaitoni, L., Perissinotto, E., Caione, L., Sanavio, F., Fagioli, F., Aglietta, M., Piacibello, W.
(2004). Fast But Durable Megakaryocyte Repopulation and Platelet Production in NOD/SCID Mice Transplanted with Ex-Vivo Expanded Human Cord Blood CD34+ Cells. Stem Cells
22: 135-143
[Abstract][Full Text]
Chute, J. P., Muramoto, G., Fung, J., Oxford, C.
(2004). Quantitative Analysis Demonstrates Expansion of SCID-Repopulating Cells and Increased Engraftment Capacity in Human Cord Blood Following Ex Vivo Culture with Human Brain Endothelial Cells. Stem Cells
22: 202-215
[Abstract][Full Text]
Mazurier, F., Gan, O. I., McKenzie, J. L., Doedens, M., Dick, J. E.
(2004). Lentivector-mediated clonal tracking reveals intrinsic heterogeneity in the human hematopoietic stem cell compartment and culture-induced stem cell impairment. Blood
103: 545-552
[Abstract][Full Text]
Denning-Kendall, P., Singha, S., Bradley, B., Hows, J.
(2003). Cobblestone Area-Forming Cells in Human Cord Blood Are Heterogeneous and Differ from Long-Term Culture-Initiating Cells. Stem Cells
21: 694-701
[Abstract][Full Text]
Chadwick, K., Wang, L., Li, L., Menendez, P., Murdoch, B., Rouleau, A., Bhatia, M.
(2003). Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood
102: 906-915
[Abstract][Full Text]
Bjornsson, J. M., Larsson, N., Brun, A. C. M., Magnusson, M., Andersson, E., Lundstrom, P., Larsson, J., Repetowska, E., Ehinger, M., Humphries, R. K., Karlsson, S.
(2003). Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient in Hoxb3 and Hoxb4. Mol. Cell. Biol.
23: 3872-3883
[Abstract][Full Text]
Murdoch, B., Chadwick, K., Martin, M., Shojaei, F., Shah, K. V., Gallacher, L., Moon, R. T., Bhatia, M.
(2003). Wnt-5A augments repopulating capacity and primitive hematopoietic development of human blood stem cells invivo. Proc. Natl. Acad. Sci. USA
100: 3422-3427
[Abstract][Full Text]
Piacibello, W., Bruno, S., Sanavio, F., Droetto, S., Gunetti, M., Ailles, L., de Sio, F. S., Viale, A., Gammaitoni, L., Lombardo, A., Naldini, L., Aglietta, M.
(2002). Lentiviral gene transfer and ex vivo expansion of human primitive stem cells capable of primary, secondary, and tertiary multilineage repopulation in NOD/SCID mice. Blood
100: 4391-4400
[Abstract][Full Text]
Chute, J. P., Saini, A. A., Chute, D. J., Wells, M. R., Clark, W. B., Harlan, D. M., Park, J., Stull, M. K., Civin, C., Davis, T. A.
(2002). Ex vivo culture with human brain endothelial cells increases the SCID-repopulating capacity of adult human bone marrow. Blood
100: 4433-4439
[Abstract][Full Text]
Jay, K. E., Gallacher, L., Bhatia, M.
(2002). Emergence of muscle and neural hematopoiesis in humans. Blood
100: 3193-3202
[Abstract][Full Text]
Kollet, O., Petit, I., Kahn, J., Samira, S., Dar, A., Peled, A., Deutsch, V., Gunetti, M., Piacibello, W., Nagler, A., Lapidot, T.
(2002). Human CD34+CXCR4- sorted cells harbor intracellular CXCR4, which can be functionally expressed and provide NOD/SCID repopulation. Blood
100: 2778-2786
[Abstract][Full Text]
Hess, D. A., Levac, K. D., Karanu, F. N., Rosu-Myles, M., White, M. J., Gallacher, L., Murdoch, B., Keeney, M., Ottowski, P., Foley, R., Chin-Yee, I., Bhatia, M.
(2002). Functional analysis of human hematopoietic repopulating cells mobilized with granulocyte colony-stimulating factor alone versus granulocyte colony-stimulating factor in combination with stem cell factor. Blood
100: 869-878
[Abstract][Full Text]
Buske, C., Feuring-Buske, M., Abramovich, C., Spiekermann, K., Eaves, C. J., Coulombel, L., Sauvageau, G., Hogge, D. E., Humphries, R. K.
(2002). Deregulated expression of HOXB4 enhances the primitive growth activity of human hematopoietic cells. Blood
100: 862-868
[Abstract][Full Text]
Glimm, H., Tang, P., Clark-Lewis, I., von Kalle, C., Eaves, C.
(2002). Ex vivo treatment of proliferating human cord blood stem cells with stroma-derived factor-1 enhances their ability to engraft NOD/SCID mice. Blood
99: 3454-3457
[Abstract][Full Text]
Grande, A., Montanari, M., Tagliafico, E., Manfredini, R., Marani, T. Z., Siena, M., Tenedini, E., Gallinelli, A., Ferrari, S.
(2002). Physiological levels of 1{alpha}, 25 dihydroxyvitamin D3 induce the monocytic commitment of CD34+ hematopoietic progenitors. J. Leukoc. Biol.
71: 641-651
[Abstract][Full Text]
Dybedal, I., Bryder, D., Fossum, A., Rusten, L. S., Jacobsen, S. E. W.
(2001). Tumor necrosis factor (TNF)-mediated activation of the p55 TNF receptor negatively regulates maintenance of cycling reconstituting human hematopoietic stem cells. Blood
98: 1782-1791
[Abstract][Full Text]
Drouet, M., Herodin, F., Norol, F., Mourcin, F., Mayol, J.F.
(2001). Cell Cycle Activation of Peripheral Blood Stem and Progenitor Cells Expanded Ex Vivo with SCF, FLT-3 Ligand, TPO, and IL-3 Results in Accelerated Granulocyte Recovery in a Baboon Model of Autologous Transplantation but G0/G1 and S/G2/M Graft Cell Content Does Not Correlate with Tranplantability. Stem Cells
19: 436-442
[Abstract][Full Text]
Ro{beta}manith, T., Schroder, B., Bug, G., Muller, P., Klenner, T., Knaus, R., Hoelzer, D., Ottmann, O.G.
(2001). Interleukin 3 Improves the Ex Vivo Expansion of Primitive Human Cord Blood Progenitor Cells and Maintains the Engraftment Potential of SCID Repopulating Cells. Stem Cells
19: 313-320
[Abstract][Full Text]
Lewis, I. D., Almeida-Porada, G., Du, J., Lemischka, I. R., Moore, K. A., Zanjani, E. D., Verfaillie, C. M.
(2001). Umbilical cord blood cells capable of engrafting in primary, secondary, and tertiary xenogeneic hosts are preserved after ex vivo culture in a noncontact system. Blood
97: 3441-3449
[Abstract][Full Text]
Karanu, F. N., Murdoch, B., Miyabayashi, T., Ohno, M., Koremoto, M., Gallacher, L., Wu, D., Itoh, A., Sakano, S., Bhatia, M.
(2001). Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells. Blood
97: 1960-1967
[Abstract][Full Text]
Perez, L. E., Rinder, H. M., Wang, C., Tracey, J. B., Maun, N., Krause, D. S.
(2001). Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production. Blood
97: 1635-1643
[Abstract][Full Text]
Appelbaum, F. R., Rowe, J. M., Radich, J., Dick, J. E.
(2001). Acute Myeloid Leukemia. ASH Education Book
2001: 62-86
[Abstract][Full Text]
Rosu-Myles, M., Gallacher, L., Murdoch, B., Hess, D. A., Keeney, M., Kelvin, D., Dale, L., Ferguson, S. S. G., Wu, D., Fellows, F., Bhatia, M.
(2000). The human hematopoietic stem cell compartment is heterogeneous for CXCR4 expression. Proc. Natl. Acad. Sci. USA
97: 14626-14631
[Abstract][Full Text]
Maguer-Satta, V., Oostendorp, R., Reid, D., Eaves, C. J.
(2000). Evidence that ceramide mediates the ability of tumor necrosis factor to modulate primitive human hematopoietic cell fates. Blood
96: 4118-4123
[Abstract][Full Text]
Glimm, H., Oh, I.-H., Eaves, C. J.
(2000). Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G2/M transit and do not reenter G0. Blood
96: 4185-4193
[Abstract][Full Text]
Salmon, P., Kindler, V., Ducrey, O., Chapuis, B., Zubler, R. H., Trono, D.
(2000). High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors. Blood
96: 3392-3398
[Abstract][Full Text]
Karanu, F. N., Murdoch, B., Gallacher, L., Wu, D. M., Koremoto, M., Sakano, S., Bhatia, M.
(2000). The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells. J. Exp. Med.
192: 1365-1372
[Abstract][Full Text]
Rosu-Myles, M., Khandaker, M., Wu, D.M., Keeney, M., Foley, S.R., Howson-Jan, K., Yee, I. C., Fellows, F., Kelvin, D., Bhatia, M.
(2000). Characterization of Chemokine Receptors Expressed in Primitive Blood Cells During Human Hematopoietic Ontogeny. Stem Cells
18: 374-381
[Abstract][Full Text]
Crooks, G. M., Hao, Q.-L., Petersen, D., Barsky, L. W., Bockstoce, D.
(2000). IL-3 Increases Production of B Lymphoid Progenitors from Human CD34+CD38- Cells. J. Immunol.
165: 2382-2389
[Abstract][Full Text]
Bryder, D., Jacobsen, S. E. W.
(2000). Interleukin-3 supports expansion of long-term multilineage repopulating activity after multiple stem cell divisions in vitro. Blood
96: 1748-1755
[Abstract][Full Text]
Kelly, P. F., Vandergriff, J., Nathwani, A., Nienhuis, A. W., Vanin, E. F.
(2000). Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein. Blood
96: 1206-1214
[Abstract][Full Text]
Zandstra, P. W., Lauffenburger, D. A., Eaves, C. J.
(2000). A ligand-receptor signaling threshold model of stem cell differentiation control: a biologically conserved mechanism applicable to hematopoiesis. Blood
96: 1215-1222
[Abstract][Full Text]
Bunting, K. D., Zhou, S., Lu, T., Sorrentino, B. P.
(2000). Enforced P-glycoprotein pump function in murine bone marrow cells results in expansion of side population stem cells in vitro and repopulating cells in vivo. Blood
96: 902-909
[Abstract][Full Text]
Kirby, S., Walton, W., Smithies, O.
(2000). Hematopoietic stem cells with controllable tEpoR transgenes have a competitive advantage in bone marrow transplantation. Blood
95: 3710-3715
[Abstract][Full Text]
Pierelli, L., Marone, M., Bonanno, G., Mozzetti, S., Rutella, S., Morosetti, R., Rumi, C., Mancuso, S., Leone, G., Scambia, G.
(2000). Modulation of bcl-2 and p27 in human primitive proliferating hematopoietic progenitors by autocrine TGF-beta 1 is a cell cycle-independent effect and influences their hematopoietic potential. Blood
95: 3001-3009
[Abstract][Full Text]
Barquinero, J., Segovia, J. C., Ramirez, M., Limon, A., Guenechea, G., Puig, T., Briones, J., Garcia, J., Bueren, J. A.
(2000). Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice. Blood
95: 3085-3093
[Abstract][Full Text]
Kollet, O., Peled, A., Byk, T., Ben-Hur, H., Greiner, D., Shultz, L., Lapidot, T.
(2000). beta 2 Microglobulin-deficient (B2mnull) NOD/SCID mice are excellent recipients for studying human stem cell function. Blood
95: 3102-3105
[Abstract][Full Text]
Rebel, V. I., Hartnett, S., Denham, J., Chan, M., Finberg, R., Sieff, C. A.
(2000). Maturation and Lineage-Specific Expression of the Coxsackie and Adenovirus Receptor in Hematopoietic Cells. Stem Cells
18: 176-182
[Abstract][Full Text]
Shimakura, Y., Kawada, H., Ando, K., Sato, T., Nakamura, Y., Tsuji, T., Kato, S., Hotta, T.
(2000). Murine Stromal Cell Line HESS-5 Maintains Reconstituting Ability of Ex Vivo-Generated Hematopoietic Stem Cells from Human Bone Marrow and Cytokine-Mobilized Peripheral Blood. Stem Cells
18: 183-189
[Abstract][Full Text]
Gallacher, L., Murdoch, B., Wu, D. M., Karanu, F. N., Keeney, M., Bhatia, M.
(2000). Isolation and characterization of human CD34-Lin- and CD34+Lin- hematopoietic stem cells using cell surface markers AC133 and CD7. Blood
95: 2813-2820
[Abstract][Full Text]
Szilvassy, S. J., Meyerrose, T. E., Grimes, B.
(2000). Effects of cell cycle activation on the short-term engraftment properties of ex vivo expanded murine hematopoietic cells. Blood
95: 2829-2837
[Abstract][Full Text]
Schiedlmeier, B., Kuhlcke, K., Eckert, H. G., Baum, C., Zeller, W. J., Fruehauf, S.
(2000). Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice. Blood
95: 1237-1248
[Abstract][Full Text]
Donahue, R. E., Wersto, R. P., Allay, J. A., Agricola, B. A., Metzger, M. E., Nienhuis, A. W., Persons, D. A., Sorrentino, B. P.
(2000). High levels of lymphoid expression of enhanced green fluorescent protein in nonhuman primates transplanted with cytokine-mobilized peripheral blood CD34+ cells. Blood
95: 445-452
[Abstract][Full Text]
Todisco, E., Suzuki, T., Srivannaboon, K., Coustan-Smith, E., Raimondi, S. C., Behm, F. G., Kitanaka, A., Campana, D.
(2000). CD38 ligation inhibits normal and leukemic myelopoiesis. Blood
95: 535-542
[Abstract][Full Text]
Dorrell, C., Gan, O. I., Pereira, D. S., Hawley, R. G., Dick, J. E.
(2000). Expansion of human cord blood CD34+CD38- cells in ex vivo culture during retroviral transduction without a corresponding increase in SCID repopulating cell (SRC) frequency: dissociation of SRC phenotype and function. Blood
95: 102-110
[Abstract][Full Text]
Verhasselt, B., Kerre, T., Naessens, E., Vanhecke, D., De Smedt, M., Vandekerckhove, B., Plum, J.
(1999). Thymic Repopulation by CD34+ Human Cord Blood Cells After Expansion in Stroma-Free Culture. Blood
94: 3644-3652
[Abstract][Full Text]
Glimm, H., Eaves, C.J.
(1999). Direct Evidence for Multiple Self-Renewal Divisions of Human In Vivo Repopulating Hematopoietic Cells in Short-Term Culture. Blood
94: 2161-2168
[Abstract][Full Text]
Shih, C.-C., Hu, M. C.-T., Hu, J., Medeiros, J., Forman, S. J.
(1999). Long-Term Ex Vivo Maintenance and Expansion of Transplantable Human Hematopoietic Stem Cells. Blood
94: 1623-1636
[Abstract][Full Text]
Kollet, O., Aviram, R., Chebath, J., ben-Hur, H., Nagler, A., Shultz, L., Revel, M., Lapidot, T.
(1999). The Soluble Interleukin-6 (IL-6) Receptor/IL-6 Fusion Protein Enhances In Vitro Maintenance and Proliferation of Human CD34+CD38-/low Cells Capable of Repopulating Severe Combined Immunodeficiency Mice. Blood
94: 923-931
[Abstract][Full Text]
Andrews, R. G., Briddell, R. A., Hill, R., Gough, M., McNiece, I. K.
(1999). Engraftment of Primates with G-CSF Mobilized Peripheral Blood CD34+ Progenitor Cells Expanded in G-CSF, SCF and MGDF Decreases the Duration and Severity of Neutropenia. Stem Cells
17: 210-218
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Brandt, J. E., Bartholomew, A. M., Fortman, J. D., Nelson, M. C., Bruno, E., Chen, L. M., Turian, J. V., Davis, T. A., Chute, J. P., Hoffman, R.
(1999). Ex Vivo Expansion of Autologous Bone Marrow CD34+ Cells With Porcine Microvascular Endothelial Cells Results in a Graft Capable of Rescuing Lethally Irradiated Baboons. Blood
94: 106-113
[Abstract][Full Text]
Piacibello, W., Sanavio, F., Severino, A., Dane, A., Gammaitoni, L., Fagioli, F., Perissinotto, E., Cavalloni, G., Kollet, O., Lapidot, T., Aglietta, M.
(1999). Engraftment in Nonobese Diabetic Severe Combined Immunodeficient Mice of Human CD34+ Cord Blood Cells After Ex Vivo Expansion: Evidence for the Amplification and Self-Renewal of Repopulating Stem Cells. Blood
93: 3736-3749
[Abstract][Full Text]
Möbest, D., Goan, S.-R., Junghahn, I., Winkler, J., Fichtner, I., Becker, M., de Lima-Hahn, E., Mertelsmann, R., Henschler, R.
(1999). Differential Kinetics of Primitive Hematopoietic Cells Assayed In Vitro and In Vivo During Serum-Free Suspension Culture of CD34+ Blood Progenitor Cells. Stem Cells
17: 152-161
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Bhatia, M., Bonnet, D., Wu, D., Murdoch, B., Wrana, J., Gallacher, L., Dick, J. E.
(1999). Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells. J. Exp. Med.
189: 1139-1148
[Abstract][Full Text]
Rebel, V. I., Tanaka, M., Lee, J.-S., Hartnett, S., Pulsipher, M., Nathan, D. G., Mulligan, R. C., Sieff, C. A.
(1999). One-Day Ex Vivo Culture Allows Effective Gene Transfer Into Human Nonobese Diabetic/Severe Combined Immune-Deficient Repopulating Cells Using High-Titer Vesicular Stomatitis Virus G Protein Pseudotyped Retrovirus. Blood
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