Podolin, P. L., Bolognese, B. J., Carpenter, D. C., Davis, T. G., Johanson, R. A., Fox, J. H., Long, E. III, Dong, X., Marquis, R. W., LoCastro, S. M., Terfloth, G. J., Kurali, E., Peterson, J. J., Smith, B. R., McQueney, M. S., Yamashita, D. S., Capper-Spudich, E. A.
(2008). Inhibition of Invariant Chain Processing, Antigen-Induced Proliferative Responses, and the Development of Collagen-Induced Arthritis and Experimental Autoimmune Encephalomyelitis by a Small Molecule Cysteine Protease Inhibitor. J. Immunol.
180: 7989-8003
[Abstract][Full Text]
Costantino, C. M., Hang, H. C., Kent, S. C., Hafler, D. A., Ploegh, H. L.
(2008). Lysosomal Cysteine and Aspartic Proteases Are Heterogeneously Expressed and Act Redundantly to Initiate Human Invariant Chain Degradation. J. Immunol.
180: 2876-2885
[Abstract][Full Text]
Young, L. J., Wilson, N. S., Schnorrer, P., Mount, A., Lundie, R. J., La Gruta, N. L., Crabb, B. S., Belz, G. T., Heath, W. R., Villadangos, J. A.
(2007). Dendritic cell preactivation impairs MHC class II presentation of vaccines and endogenous viral antigens. Proc. Natl. Acad. Sci. USA
104: 17753-17758
[Abstract][Full Text]
Kakehashi, H., Nishioku, T., Tsukuba, T., Kadowaki, T., Nakamura, S., Yamamoto, K.
(2007). Differential Regulation of the Nature and Functions of Dendritic Cells and Macrophages by Cathepsin E. J. Immunol.
179: 5728-5737
[Abstract][Full Text]
Soualhine, H., Deghmane, A.-E., Sun, J., Mak, K., Talal, A., Av-Gay, Y., Hmama, Z.
(2007). Mycobacterium bovis Bacillus Calmette-Guerin Secreting Active Cathepsin S Stimulates Expression of Mature MHC Class II Molecules and Antigen Presentation in Human Macrophages. J. Immunol.
179: 5137-5145
[Abstract][Full Text]
Majlessi, L., Combaluzier, B., Albrecht, I., Garcia, J. E., Nouze, C., Pieters, J., Leclerc, C.
(2007). Inhibition of Phagosome Maturation by Mycobacteria Does Not Interfere with Presentation of Mycobacterial Antigens by MHC Molecules. J. Immunol.
179: 1825-1833
[Abstract][Full Text]
Majewski, M., Bose, T. O., Sille, F. C. M., Pollington, A. M., Fiebiger, E., Boes, M.
(2007). Protein kinase C delta stimulates antigen presentation by Class II MHC in murine dendritic cells. Int Immunol
19: 719-732
[Abstract][Full Text]
Choe, Y., Leonetti, F., Greenbaum, D. C., Lecaille, F., Bogyo, M., Bromme, D., Ellman, J. A., Craik, C. S.
(2006). Substrate Profiling of Cysteine Proteases Using a Combinatorial Peptide Library Identifies Functionally Unique Specificities. J. Biol. Chem.
281: 12824-12832
[Abstract][Full Text]
Wang, Y., Baron, R. M., Zhu, G., Joo, M., Christman, J. W., Silverman, E. S., Perrella, M. A., Riese, R. J., Cernadas, M.
(2006). PU.1 Regulates Cathepsin S Expression in Professional APCs. J. Immunol.
176: 275-283
[Abstract][Full Text]
Becker-Herman, S., Arie, G., Medvedovsky, H., Kerem, A., Shachar, I.
(2005). CD74 Is a Member of the Regulated Intramembrane Proteolysis-processed Protein Family. Mol. Biol. Cell
16: 5061-5069
[Abstract][Full Text]
Sendide, K., Deghmane, A.-E., Pechkovsky, D., Av-Gay, Y., Talal, A., Hmama, Z.
(2005). Mycobacterium bovis BCG Attenuates Surface Expression of Mature Class II Molecules through IL-10-Dependent Inhibition of Cathepsin S. J. Immunol.
175: 5324-5332
[Abstract][Full Text]
Maehr, R., Hang, H. C., Mintern, J. D., Kim, Y.-M., Cuvillier, A., Nishimura, M., Yamada, K., Shirahama-Noda, K., Hara-Nishimura, I., Ploegh, H. L.
(2005). Asparagine Endopeptidase Is Not Essential for Class II MHC Antigen Presentation but Is Required for Processing of Cathepsin L in Mice. J. Immunol.
174: 7066-7074
[Abstract][Full Text]
Chain, B. M., Free, P., Medd, P., Swetman, C., Tabor, A. B., Terrazzini, N.
(2005). The Expression and Function of Cathepsin E in Dendritic Cells. J. Immunol.
174: 1791-1800
[Abstract][Full Text]
Yang, H., Kala, M., Scott, B. G., Goluszko, E., Chapman, H. A., Christadoss, P.
(2005). Cathepsin S Is Required for Murine Autoimmune Myasthenia Gravis Pathogenesis. J. Immunol.
174: 1729-1737
[Abstract][Full Text]
Lautwein, A., Kraus, M., Reich, M., Burster, T., Brandenburg, J., Overkleeft, H. S., Schwarz, G., Kammer, W., Weber, E., Kalbacher, H., Nordheim, A., Driessen, C.
(2004). Human B lymphoblastoid cells contain distinct patterns of cathepsin activity in endocytic compartments and regulate MHC class II transport in a cathepsin S-independent manner. J. Leukoc. Biol.
75: 844-855
[Abstract][Full Text]
Wilson, N. S., El-Sukkari, D., Villadangos, J. A.
(2004). Dendritic cells constitutively present self antigens in their immature state in vivo and regulate antigen presentation by controlling the rates of MHC class II synthesis and endocytosis. Blood
103: 2187-2195
[Abstract][Full Text]
Golden, J. W., Bahe, J. A., Lucas, W. T., Nibert, M. L., Schiff, L. A.
(2004). Cathepsin S Supports Acid-independent Infection by Some Reoviruses. J. Biol. Chem.
279: 8547-8557
[Abstract][Full Text]
Thurmond, R. L., Sun, S., Sehon, C. A., Baker, S. M., Cai, H., Gu, Y., Jiang, W., Riley, J. P., Williams, K. N., Edwards, J. P., Karlsson, L.
(2004). Identification of a Potent and Selective Noncovalent Cathepsin S Inhibitor. J. Pharmacol. Exp. Ther.
308: 268-276
[Abstract][Full Text]
Musson, J. A., Walker, N., Flick-Smith, H., Williamson, E. D., Robinson, J. H.
(2003). Differential Processing of CD4 T-cell Epitopes from the Protective Antigen of Bacillus anthracis. J. Biol. Chem.
278: 52425-52431
[Abstract][Full Text]
El-Sukkari, D., Wilson, N. S., Hakansson, K., Steptoe, R. J., Grubb, A., Shortman, K., Villadangos, J. A.
(2003). The Protease Inhibitor Cystatin C Is Differentially Expressed among Dendritic Cell Populations, but Does Not Control Antigen Presentation. J. Immunol.
171: 5003-5011
[Abstract][Full Text]
Koonce, C. H., Wutz, G., Robertson, E. J., Vogt, A. B., Kropshofer, H., Bikoff, E. K.
(2003). DM Loss in k Haplotype Mice Reveals Isotype-Specific Chaperone Requirements. J. Immunol.
170: 3751-3761
[Abstract][Full Text]
Greiner, A., Lautwein, A., Overkleeft, H. S., Weber, E., Driessen, C.
(2003). Activity and subcellular distribution of cathepsins in primary human monocytes. J. Leukoc. Biol.
73: 235-242
[Abstract][Full Text]
Ye, Q., Finn, P. W., Sweeney, R., Bikoff, E. K., Riese, R. J.
(2003). MHC Class II-Associated Invariant Chain Isoforms Regulate Pulmonary Immune Responses. J. Immunol.
170: 1473-1480
[Abstract][Full Text]
Cebulla, C. M., Miller, D. M., Zhang, Y., Rahill, B. M., Zimmerman, P., Robinson, J. M., Sedmak, D. D.
(2002). Human Cytomegalovirus Disrupts Constitutive MHC Class II Expression. J. Immunol.
169: 167-176
[Abstract][Full Text]
Honey, K., Nakagawa, T., Peters, C., Rudensky, A.
(2002). Cathepsin L Regulates CD4+ T Cell Selection Independently of Its Effect on Invariant Chain: A Role in the Generation of Positively Selecting Peptide Ligands. J. Exp. Med.
195: 1349-1358
[Abstract][Full Text]
Storm van's Gravesande, K., Layne, M. D., Ye, Q., Le, L., Baron, R. M., Perrella, M. A., Santambrogio, L., Silverman, E. S., Riese, R. J.
(2002). IFN Regulatory Factor-1 Regulates IFN-{gamma}-Dependent Cathepsin S Expression. J. Immunol.
168: 4488-4494
[Abstract][Full Text]
Tompkins, S. M., Padilla, J., Dal Canto, M. C., Ting, J. P.-Y., Van Kaer, L., Miller, S. D.
(2002). De Novo Central Nervous System Processing of Myelin Antigen Is Required for the Initiation of Experimental Autoimmune Encephalomyelitis. J. Immunol.
168: 4173-4183
[Abstract][Full Text]
Hsieh, C.-S., deRoos, P., Honey, K., Beers, C., Rudensky, A. Y.
(2002). A Role for Cathepsin L and Cathepsin S in Peptide Generation for MHC Class II Presentation. J. Immunol.
168: 2618-2625
[Abstract][Full Text]
Nishioku, T., Hashimoto, K., Yamashita, K., Liou, S.-Y., Kagamiishi, Y., Maegawa, H., Katsube, N., Peters, C., von Figura, K., Saftig, P., Katunuma, N., Yamamoto, K., Nakanishi, H.
(2002). Involvement of Cathepsin E in Exogenous Antigen Processing in Primary Cultured Murine Microglia. J. Biol. Chem.
277: 4816-4822
[Abstract][Full Text]
Bikoff, E. K., Wutz, G., Kenty, G. A., Koonce, C. H., Robertson, E. J.
(2001). Relaxed DM Requirements During Class II Peptide Loading and CD4+ T Cell Maturation in BALB/c Mice. J. Immunol.
166: 5087-5098
[Abstract][Full Text]
Fiebiger, E., Meraner, P., Weber, E., Fang, I-F., Stingl, G., Ploegh, H., Maurer, D.
(2001). Cytokines Regulate Proteolysis in Major Histocompatibility Complex Class II-dependent Antigen Presentation by Dendritic Cells. J. Exp. Med.
193: 881-892
[Abstract][Full Text]
Shi, G.-P., Bryant, R. A.R., Riese, R., Verhelst, S., Driessen, C., Li, Z., Bromme, D., Ploegh, H. L., Chapman, H. A.
(2000). Role for Cathepsin F in Invariant Chain Processing and Major Histocompatibility Complex Class II Peptide Loading by Macrophages. J. Exp. Med.
191: 1177-1186
[Abstract][Full Text]
Denis, F., Shoukry, N. H., Delcourt, M., Thibodeau, J., Labrecque, N., McGrath, H., Munzer, J. S., Seidah, N. G., Sékaly, R.-P.
(2000). Alternative Proteolytic Processing of Mouse Mammary Tumor Virus Superantigens. J. Virol.
74: 3067-3073
[Abstract][Full Text]
Wolters, P. J., Laig-Webster, M., Caughey, G. H.
(2000). Dipeptidyl Peptidase I Cleaves Matrix-Associated Proteins and Is Expressed Mainly by Mast Cells in Normal Dog Airways. Am. J. Respir. Cell Mol. Bio.
22: 183-190
[Abstract][Full Text]
Driessen, C., Bryant, R. A.R., Lennon-Dumenil, A.-M., Villadangos, J. A., Bryant, P. W., Shi, G.-P., Chapman, H. A., Ploegh, H. L.
(1999). Cathepsin S Controls the Trafficking and Maturation of MHC Class II Molecules in Dendritic Cells. J. Cell Biol.
147: 775-790
[Abstract][Full Text]
Kenty, G., Bikoff, E. K.
(1999). BALB/c Invariant Chain Mutant Mice Display Relatively Efficient Maturation of CD4+ T Cells in the Periphery and Secondary Proliferative Responses Elicited upon Peptide Challenge. J. Immunol.
163: 232-241
[Abstract][Full Text]
Baker, C. A., Lu, Z. Y., Zaitsev, I., Manuelidis, L.
(1999). Microglial Activation Varies in Different Models of Creutzfeldt-Jakob Disease. J. Virol.
73: 5089-5097
[Abstract][Full Text]
Wang, B., Shi, G.-P., Yao, P. M., Li, Z., Chapman, H. A., Bromme, D.
(1998). Human Cathepsin F. MOLECULAR CLONING, FUNCTIONAL EXPRESSION, TISSUE LOCALIZATION, AND ENZYMATIC CHARACTERIZATION. J. Biol. Chem.
273: 32000-32008
[Abstract][Full Text]
Maurer, D., Fiebiger, E., Reininger, B., Ebner, C., Petzelbauer, P., Shi, G.-P., Chapman, H. A., Stingl, G.
(1998). Fc{epsilon} Receptor I on Dendritic Cells Delivers IgE-Bound Multivalent Antigens into a Cathepsin S-Dependent Pathway of MHC Class II Presentation. J. Immunol.
161: 2731-2739
[Abstract][Full Text]
Nakagawa, T., Roth, W., Wong, P., Nelson, A., Farr, A., Deussing, J., Villadangos, J. A., Ploegh, H., Peters, C., Rudensky, A. Y.
(1998). Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus. Science
280: 450-453
[Abstract][Full Text]
Deussing, J., Roth, W., Saftig, P., Peters, C., Ploegh, H. L., Villadangos, J. A.
(1998). Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc. Natl. Acad. Sci. USA
95: 4516-4521
[Abstract][Full Text]
Bikoff, E. K., Kenty, G., Van Kaer, L.
(1998). Distinct Peptide Loading Pathways for MHC Class II Molecules Associated with Alternative Ii Chain Isoforms. J. Immunol.
160: 3101-3110
[Abstract][Full Text]
Walter, W., Scheuer, C., Loos, M., Reichert, T. E., Maeurer, M. J.
(2001). H2-Mbeta 1 and H2-Mbeta 2 Heterodimers Equally Promote CLIP Removal in I-Aq Molecules from Autoimmune-prone DBA/1 Mice. J. Biol. Chem.
276: 11086-11091
[Abstract][Full Text]
Neumann, J., Schach, N., Koch, N.
(2001). Glycosylation Signals That Separate the Trimerization from the MHC Class II-binding Domain Control Intracellular Degradation of Invariant Chain. J. Biol. Chem.
276: 13469-13475
[Abstract][Full Text]
Honey, K., Duff, M., Beers, C., Brissette, W. H., Elliott, E. A., Peters, C., Maric, M., Cresswell, P., Rudensky, A.
(2001). Cathepsin S Regulates the Expression of Cathepsin L and the Turnover of gamma -Interferon-inducible Lysosomal Thiol Reductase in B Lymphocytes. J. Biol. Chem.
276: 22573-22578
[Abstract][Full Text]