The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 172, 1263-1266, Copyright © 1990 by Rockefeller University Press


ARTICLES

Expression of gamma/delta T cell receptors on lymphocytes from the lactating mammary gland

C Reardon, L Lefrancois, A Farr, R Kubo, R O'Brien and W Born
Department of Dermatology, University of Colorado Health Sciences Center, Denver 80262.

gamma/delta cells were at least four times more frequent in lactating mouse mammary glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly isolated T cells and a study of clonally expressed gamma/delta receptors on hybridomas further revealed that the mammary gamma/delta population is heterogeneous, including at least three different subsets, among them cells expressing V gamma 5, V gamma 4 together with V delta 4, or none of these V regions.
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