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Journal of Experimental Medicine, Vol 158, 1374-1379, Copyright © 1983 by Rockefeller University Press
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RW Karr, CC Kannapell, RJ Zangara, SM Goyert, J Silver and BD Schwartz
Previous studies have indicated that LLA-DR homozygous cell lines express two DR molecules but only a single DS (I-A-like) molecule. This report demonstrates that an HLA-DR5 homozygous cell line expresses at least two distinct DS molecules. These two DS molecules are formed by the association of a single DS alpha chain with either of two DS beta chains. Four distinct Ia molecules have now been identified from this DR5 homozygous cell line.
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