The Journal of Experimental Medicine
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Journal of Experimental Medicine, Vol 154, 204-209, Copyright © 1981 by Rockefeller University Press

ARTICLES

Enhancement of delayed hypersensitivity reaction with varieties of anti- cancer drugs. A common biological phenomenon

M Goto, A Mitsuoka, M Sugiyama and M Kitano

Delayed hypersensitivity reaction in mice was commonly enhanced with various anti-cancer agents administered as single or intermittent high doses but not consecutive divided doses. The effect of anti-cancer agents on the delayed hypersensitivity reaction was thought to be due to elimination of suppressor T cell activity.
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