The Journal of Experimental Medicine
Symposium on Dendritic Cells
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Journal of Experimental Medicine, Vol 151, 400-406, Copyright © 1980 by Rockefeller University Press


ARTICLES

Isolation and partial characterization of the human homologue of Thy-1

EW Ades, RK Zwerner, RT Acton and CM Balch

A glycoprotein of 25,000 daltons was isolated from a human T lymphoblastoid cell line (MOLT-3). A monovalent antiserum raised against this antigen precipitated mouse Thy-1.1 antigen as well as a 25,000-dalton antigen from human blood T cells. The unabsorbed serum was also cytotoxic for both mouse and human T cells. By multiple criteria, this human T antigen appears to be homologous with mouse Thy- 1.
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