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Journal of Experimental Medicine, Vol 148, 1711-1715, Copyright © 1978 by Rockefeller University Press
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U Kees, A Mullbacher and RV Blanden
These experiments tested whether Tc cells specific for foreign antigen (X) plus self H-2 adsorbed to macrophage monolayers displaying (a) X with allogeneic H-2; (B) self H-2 alone; (c) X plus self H-2. Specific adsorption occurred only in case (c), a result compatible with altered self and requiring further operational assumptions in dual recognition models.
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