The Journal of Experimental Medicine
StemCell Technologies
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Journal of Experimental Medicine, Vol 146, 1143-1145, Copyright © 1977 by Rockefeller University Press

ARTICLES

Antigens expressed by human B lymphocytes and myeloid stem cells

MJ Cline and R Billing

Antisera prepared against papain-digested spleen cell membranes were known to by cytotoxic for normal and neoplastic human B lymphocytes and for a majority of acute and chronic myeloid leukemic cells. It is now shown that these antisera are also cytotoxic for normal myeloid stem cells (CFU-C), thus providing a probable explanation for their occurrence in myeloid neoplasia.
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