The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 139, 1070-1076, Copyright © 1974 by The Rockefeller University Press

ARTICLE

EPSTEIN-BARR VIRUS-NEGATIVE HUMAN MALIGNANT T-CELL LINES

Joseph Kaplan 1, Thomas C. Shope 1, and Ward D. Peterson Jr. 1

1 From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

Two lymphoblastoid lines, CCRF-CEM and HSB-2, with properties of malignant cells, derived from children with leukemia secondary to lymphosarcoma, have T-cell properties and lack Epstein-Barr virus antigens.

Submitted on January 21, 1974


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