The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 139, 313-322, Copyright © 1974 by The Rockefeller University Press

ARTICLE

ELECTROPHORETIC MOBILITY AND AGGLUTINABILITY OF RED BLOOD CELLS: A "NEW" POLYMORPHISM IN MICE

Pablo Rubinstein 1, Ngukoy Liu 1, Edwin W. Streun 1, and Francine Decary 1

1 From the Serology and Genetics Division, The New York Blood Center, New York 10021, and the Department of Pathology, Mt. Sinai School of Medicine, City University of New York, New York 10029

A quantitative method has been developed to determine agglutinability of mouse red blood cells. Tests with different inbred strains of mice revealed only two phenotypes. The same inbred strains were tested with the cytopherometer to determine the electrophoretic mobility of the corresponding red cells. Again, two phenotypes were uncovered, and faster mobility was found in the red cells that had higher agglutinability. The genetic control of this character is autosomal and codominant, and segregates independently of H-2 and coat color.

Submitted on October 26, 1973


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