The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 136, 409-414, Copyright © 1972 by The Rockefeller University Press

BRIEF DEFINITIVE REPORTS

CLASS, SUBCLASS, AND ALLELIC EXCLUSION OF MEMBRANE-BOUND Ig OF HUMAN B LYMPHOCYTES

S. S. Fröland 1 and J. B. Natvig 1

1 From the Institute of Immunology and Rheumatology, Oslo, Norway

Membrane-bound immunoglobulins of peripheral blood B lymphocytes and of lymphocytes from an IgG chronic lymphocytic leukemia showed restriction to one immunoglobulin class, one IgG subclass, and one Gm allotype. Certain antigens in the C-terminal part of IgG Fc were not exposed on the cell surface.

Submitted on May 11, 1972


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