Gideon Berke ¹ and Raphael H. Levey ¹

¹ From the Department of Surgery, Harvard Medical School, and the Children's Hospital Medical Center, Boston, Massachusetts 02115

Mouse lymphoid cells, sensitized against tumor allografts, can be deprived of the immunoreactive cells by in vitro absorption with specific fibroblast monolayers. Populations of lymphocytes so depleted are less effective in retarding tumor growth in vivo and in lysing tumor cells in vitro. Moreover, the adsorbed immunoreactive cells can be recovered specifically and are subsequently efficient in inhibiting tumor growth in vivo and in killing tumor cells in vitro.

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