The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 135, 711-717, Copyright © 1972 by The Rockefeller University Press

BRIEF DEFINITIVE REPORT

CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE : VIII. RADIOSENSITIVITY OF THYMUS-DERIVED LYMPHOCYTES



R. E. Anderson 1, J. Sprent 1, and J. F. A. P. Miller 1

1 From the Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia

The helper function of carrier-primed T cells was found to be radiosensitive in vivo. The results could not be attributed to interference with the spleen-seeking properties of the irradiated cells. It is suggested that T cell division is essential for the induction of 7S antibody responses in vivo.

Submitted on January 4, 1972


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