The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 134, 330-336, Copyright © 1971 by The Rockefeller University Press

RHEUMATOID ARTHRITIS AND OTHER DISEASES

VASCULITIS IN ASSOCIATION WITH AUSTRALIA ANTIGEN

David J. Gocke 1, Konrad Hsu 1, Councilman Morgan 1, Stepheno Bombardieri 1, Michael Lockshin 1, and Charles L. Christian 1

1 From the Department of Medicine, College of Physicians and Surgeons of Columbia University, New York 10032

Six patients with biopsy-proven polyarteritis nodosa and chronic Australia antigenemia are described. Evidence was found in these patients for the presence of circulating immune complexes composed of Australia antigen and immunoglobulin. In addition, in two patients immunofluorescent studies localized Australia antigen, IgM, and complement in the blood vessel walls.


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