The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 132, 694-701, Copyright © 1970 by The Rockefeller University Press

ARTICLE

STUDIES OF THE RELATIONSHIP BETWEEN THE PRODUCTION OF BACTERIOCINES BY GROUP A STREPTOCOCCI AND ACUTE GLOMERULONEPHRITIS

Gary D. Overturf M.D.1 and Edward A. Mortimer Jr. M.D.1

1 From the Department of Pediatrics, University of New Mexico School of Medicine, Albuquerque, New Mexico 87106

The previously reported relationship between nephritogenicity and bacteriocine production among Group A streptococci has been examined. Using techniques comparable to the earlier study, the present study did not reveal any such relationship. Among 73 strains tested, 53% produced bacteriocines; no significant difference was noted between bacteriocines from strains isolated from cases of nephritis and those from a group of strains recovered from patients with other conditions. In addition, no correlation between type and bacteriocine production was observed.

Submitted on May 29, 1970


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