The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 116, 653-664, ©Copyright, 1962, by The Rockefeller Institute

ARTICLE

SUPPRESSION OF ALLERGIC UVEITIS BY 6-MERCAPTOPURINE

E. Wirostko M.D.1 and S. P. Halbert M.D.1

1 From the Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York

Experimental uveitis in rabbits was induced by single intraocular antigen injection. Treatment with 6-MP for 14 days suppressed the allergic inflammation and antibody response. A good correlation was demonstrated between the degree of uveitis and the antibody titer.

Submitted on July 2, 1962


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