The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
  Home | Help | Feedback | Subscriptions | Archive | Search | Table of Contents
This Article
Right arrow Full Text (PDF, 548K)
Right arrow Alert me when this article is cited
Services
Right arrow Email this article
Right arrow Similar articles in this journal
Right arrow Alert me to new content in the JEM
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Takahashi, Y.
Right arrow Articles by Nagayama, Y.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Takahashi, Y.
Right arrow Articles by Nagayama, Y.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati  
What's this?
The Journal of Experimental Medicine, Vol 114, 569-579, Copyright, 1961, by The Rockefeller Institute

ARTICLE

THE BEHAVIOR OF THREE DIFFERENT KINDS OF ANTIBODIES IN TUBERCULOSIS: ANTIPROTEIN, ANTIPOLYSACCHARIDE, AND ANTIPHOSPHATIDE : II. HUMAN TUBERCULOSIS



Yoshio Takahashi M.D.1, Koji Mochizuki M.D.1, and Yoshitame Nagayama M.D.1

1 From the Research Institute for Tuberculosis, Hokkaido University, Sapporo, Hokkaido, and the Second National Sanatorium, Hokkaido, Japan

In human tuberculosis as in experimental tuberculosis, there exist in the serum of tuberculous patients three different kinds of antibodies completely distinct from each other, antipolysaccharide, antiprotein, and antiphosphatide. The two former antibodies are produced whenever tuberculous infection takes place or exists and they persist for a long period, even though tuberculous disease be arrested. On the contrary, the production of the antiphosphatide seems to be mainly conditioned by the outbreak of tuberculous disease following infection, because none of the tuberculin-positive healthy persons tested gave a positive phosphatide hemagglutination test. The antiphosphatide hemagglutination test furnishes useful information about the extent or the activity of tuberculous disease.

No correlation was noticed between the degree of tuberculin skin hypersensitivity and the amount of any of the three antibodies.

The usefulness of the phosphatide hemagglutination test in the diagnosis of tuberculosis is discussed.

 Submitted on May 9, 1961


Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati    What's this?




  Home | Help | Feedback | Subscriptions | Archive | Search
TABLE OF CONTENTS