The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 112, 65-76, Copyright, 1960, by The Rockefeller Institute

ARTICLE

DELAYED HYPERSENSITIVITY : V. THE EFFECT OF X-IRRADIATION ON THE DEVELOPMENT OF DELAYED HYPERSENSITIVITY AND ANTIBODY FORMATION



Jonathan W. Uhr M.D.1 and Matthew Scharff M.D.1

1 From the Departments of Microbiology and Medicine, New York University College of Medicine, New York

The capacity to develop the delayed type of hypersensitivity to diphtheria toxoid and ovalbumin may persist in guinea pigs and rabbits that have received doses of x-ray sufficient to eliminate a detectable antibody response. Larger doses of x-irradiation can prevent development of delayed-type hypersensitivity in rabbits.

Submitted on February 11, 1960


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