The Journal of Experimental Medicine
Janeway's Immunobiology 7th Edition
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The Journal of Experimental Medicine, Vol 108, 797-802, Copyright, 1958, by The Rockefeller Institute

ARTICLE

AN INFECTIOUS CUTANEOUS FIBROMA OF THE VIRGINIA WHITE-TAILED DEER (ODOCOILEUS VIRGINIANUS)

Richard E. Shope M.D.1, Robert Mangold 1, Lester G. MacNamara 1, and Keith R. Dumbell M.D.1

1 From The Rockefeller Institute; State of New Jersey Department of Conservation and Economic Development, Division of Fish and Game, Trenton; and Department of Bacteriology, The University, Liverpool

A naturally occurring cutaneous fibroma of deer has proven to be experimentally transmissible in deer. The causative agent is a virus that is readily alterable through Berkefeld N candles and that survives in fibroma tissue for at least as long as 27 months in glycerol-saline at –20°C. The experimentally produced deer fibroma has an incubation period of about 7 weeks, a very slow rate of growth, and a high regression rate.

Submitted on July 21, 1958


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