The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 106, 777-786, Copyright, 1957, by The Rockefeller Institute for Medical Research New York

ARTICLE

FATE OF NON-VIRULENT GROUP A STREPTOCOCCI PHAGOCYTIZED BY HUMAN AND MOUSE NEUTROPHILS

Armine T. Wilson M.D.1, Grove G. Wiley M.D.1, and Pauline Bruno 1

1 From the Alfred I. du Pont Institute of the Nemours Foundation, Wilmington, Delaware

The fate of non-virulent group A streptococci phagocytized in vitro has been investigated by destroying the phagocyte with electric current and observing whether the liberated cocci multiply.

Human and mouse peripheral blood neutrophils quickly injure ingested cocci, the time required to produce 50 per cent non-survival of chains being 8 and 6frac34 minutes, respectively.

 Submitted on July 26, 1957


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