The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 105, 403-415, Copyright, 1957, by The Rockefeller Institute for Medical Research New York

ARTICLE

QUANTITATIVE STUDIES ON THE PROPERDIN-COMPLEMENT SYSTEM : II. KINETICS OF THE REACTION BETWEEN PROPERDIN AND ZYMOSAN



Myron A. Leon Ph.D.1 and With the Technical Assistance of Edna Chapman and Arnold Ransby

1 From the Department of Surgical Research, Saint Luke's Hospital, Cleveland

The reaction of human, bovine, and pig properdin with excess zymosan exhibits an induction period followed by a rapidly accelerating formation of the properdin-zymosan (PZ) complex. Two methods for determining the quantity of PZ complex are given, one using human serum lacking properdin, the other using a fraction of pig serum containing complement components, C'1, C'3 and C'4.

Submitted on January 10, 1957


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