The Journal of Experimental Medicine
Accuri Cytometers
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The Journal of Experimental Medicine, Vol 103, 301-307, Copyright, 1956, by The Rockefeller Institute for Medical Research New York

ARTICLE

THE PURIFICATION OF HYPERTENSIN II

Leonard T. Skeggs Jr. Ph.D.1, Joseph R. Kahn M.D.1, and Norman P. Shumway M.D.1

1 From the Department of Medicine and Surgery, Veterans Administration Hospital, and the Department of Pathology, Western Reserve University, Cleveland

The enzymatic conversion of hypertensin I to hypertensin II is described together with the subsequent purification of the product by means of counter-current distribution.

Improved methods are also presented for the preparation of renin and its substrate, as well as in methods for the reaction of these materials and the purification of the resulting hypertensin I.

 Submitted on December 12, 1955


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