The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 102, 783-788, Copyright, 1955, by The Rockefeller Institute for Medical Research New York

ARTICLE

MITOCHONDRIAL CHANGES INDUCED BY POTASSIUM AND SODIUM IN THE DUODENAL ABSORPTIVE CELL AS STUDIED WITH THE ELECTRON MICROSCOPE

Jules M. Weiss M.D.1 and With Technical Assistance of Doris Fleisch

1 From the Department of Anatomy, Washington University School of Medicine, St. Louis

Duodenal absorptive cells from animals fed large amounts of sodium or potassium contain many mitochondria with internal granules. Many mitochondrial granules are also present in cells which transport large amounts of cation. The hypothesis is advanced that the mitochondrial granule represents cation segregated within the mitochondrion. A mechanism is suggested for the segregation of excessive intracellular potassium, and for the transport of cations across cells.

Submitted on July 5, 1955


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