The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 102, 403-411, Copyright, 1955, by The Rockefeller Institute for Medical Research New York

ARTICLE

STUDIES ON SUSCEPTIBILITY TO INFECTION FOLLOWING IONIZING RADIATION : III. SUSCEPTIBILITY OF THE INTESTINAL TRACT TO ORAL INOCULATION WITH PSEUDOMONAS AERUGINOSA



Carolyn W. Hammond Ph.D.1, David Ruml M.D.1, Dorothy B. Cooper 1, and C. Phillip Miller M.D.1

1 From the Department of Medicine, The University of Chicago, Chicago

Pseudomonas aeruginosa introduced directly into the stomach established itself more regularly in the intestinal tract of irradiated mice than of unirradiated mice. The irradiated mice had been exposed to 550 r total body x-irradiation 5 days before inoculation.

This difference between irradiated and unirradiated mice could not be explained by differences in pH of gastric or duodenal contents, propulsive motility of the intestinal tract, or the ability of the intestinal contents to support growth of Pseudomonas in vitro.

 Submitted on May 27, 1955


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