The Journal of Experimental Medicine
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The Journal of Experimental Medicine, Vol 102, 151-156, Copyright, 1955, by The Rockefeller Institute for Medical Research New York

ARTICLE

EFFECT OF ETHIONINE-INDUCED PANCREATIC DAMAGE ON IRON ABSORPTION

Thomas D. Kinney M.D.1, Nathan Kaufman M.D.1, and Janis Klavins M.D.1

1 From the Departments of Pathology, Cleveland City Hospital, and Western Reserve University School of Medicine, Cleveland

Groups of rats were fed a diet of the purified type which was supplemented by dl-ethionine to produce pancreatic damage. It was shown that animals with pancreatic damage absorbed more iron from the gastrointestinal tract than control animals without pancreatic damage. When iron was added to the diet the animals with pancreatic damage absorbed even greater quantities of iron. These findings in rats were corroborated by similar findings in mice.

Submitted on May 6, 1955


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